Selected Literature

Epicardial FSTL1 reconstitution regenerates the adult mammalian heart.

Wei K, Serpooshan V, Hurtado C, Diez-Cuñado M, Zhao M, Maruyama S, Zhu W, Fajardo G, Noseda M, Nakamura K, Tian X, Liu Q, Wang A, Matsuura Y, Bushway P, Cai W, Savchenko A, Mahmoudi M, Schneider MD, van den Hoff MJ, Butte MJ, Yang PC, Walsh K, Zhou B, Bernstein D, Mercola M, Ruiz-Lozano P.

2015 Sep 24;525(7570):479-85. doi: 10.1038/nature15372. Epub 2015 Sep 16.
PMID: 26375005

Cardiac Repair after Myocardial Infarction

Van Rooij E.

N Engl J Med. 2016 Jan 7;374(1):85-7. doi: 10.1056/NEJMcibr1512011. No abstract available.
PMID: 26735998

Ablation of a Single N-Glycosylation Site in Human FSTL 1 Induces Cardiomyocyte Proliferation and Cardiac Regeneration.

Magadum A, Singh N, Kurian AA, Sharkar MTK, Chepurko E, Zangi L.

Mol Ther Nucleic Acids. 2018;13:133-43. Epub 2018/10/06. doi: 10.1016/j.omtn.2018.08.021.
PubMed PMID: 30290305; PMCID: PMC6171324.

Single intracoronary injection of encapsulated antagomir-92a promotes angiogenesis and prevents adverse infarct remodeling.

Bellera N, Barba I, Rodriguez-Sinovas A, Ferret E, Asin MA, Gonzalez-Alujas MT, Perez-Rodon J, Esteves M, Fonseca C, Toran N, Garcia Del Blanco B, Perez A, Garcia-Dorado D. J

Am Heart Assoc. 2014;3(5):e000946. doi: 10.1161/JAHA.114.000946.
PubMed PMID: 25240056; PMCID: PMC4323815

FSTL1 as a Potential Mediator of Exercise-Induced Cardioprotection in Post-Myocardial Infarction Rats.

Xi Y, Gong DW, Tian Z.

Sci Rep. 2016 Aug 26;6:32424. doi: 10.1038/srep32424.
PMID: 27561749

Follistatin-like 1-engineered mesenchymal stem cells prevent myocardial ischemic reperfusion injury.

Zhang MQ, Chen H, Zhai CL, Tu JF, Shen Y, Pang LX, Xu QR.

Zhonghua Yi Xue Za Zhi. 2016 Jul 5;96(25):2017-22. doi: 10.3760/cma.j.issn.0376-2491.2016.25.013. Chinese.
PMID: 27470962

Follistatin like 1 Regulates Hypertrophy in Heart Failure with Preserved Ejection Fraction.

Tanaka K, Valero-Muñoz M, Wilson RM, Essick EE, Fowler CT, Nakamura K, van den Hoff M, Ouchi N, Sam F.

JACC Basic Transl Sci. 2016 Jun;1(4):207-221. doi: 10.1016/j.jacbts.2016.04.002. Epub 2016 Jun 27.
PMID: 27430031

Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture.

Maruyama S, Nakamura K, Papanicolaou KN, Sano S, Shimizu I, Asaumi Y, van den Hoff MJ, Ouchi N, Recchia FA, Walsh K.

EMBO Mol Med. 2016 Aug 1;8(8):949-66. doi: 10.15252/emmm.201506151. Print 2016 Aug.
PMID: 27234440

Overexpressing FSTL1 for Heart Repair.

Sanchis-Gomar F, Perez-Quilis C, Lucia A.

Trends Mol Med. 2016 May;22(5):353-4. doi: 10.1016/j.molmed.2016.03.003. Epub 2016 Mar 26.
PMID: 27025407

Follistatin-like 1 protects cardiomyoblasts from injury induced by sodium nitroprusside through modulating Akt and Smad1/5/9 signaling.

Chen W, Xia J, Hu P, Zhou F, Chen Y, Wu J, Lei W, Shen Z.

Biochem Biophys Res Commun. 2016 Jan 15;469(3):418-23. doi: 10.1016/j.bbrc.2015.12.026. Epub 2015 Dec 10.
PMID: 26687945